Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537279 | 0.86 | ADORA3 (0.43) | KDM4EHTTSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9538217 | 0.77 | CYP11B1 (0.39) | KDM4EHTTSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9538692 | 0.74 | ADORA3 (0.42) | KDM4EHTTSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9538271 | 0.73 | ADORA3 (0.40) | KDM4EHTTSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9540686 | 0.73 | HTR2A (0.37) | KDM4EHSD17B3AVPR1AOXTR | |
| SCHEMBL9537919 | 0.72 | AVPR1A (0.40) | KDM4EBRD4HSD17B3ALDH1A1AVPR1A | |
| SCHEMBL9537519 | 0.72 | ADORA3 (0.41) | KDM4EHTTSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9535510 | 0.72 | BRD4 (0.37) | BRD4HSD17B3 | |
| SCHEMBL9540537 | 0.71 | ADORA3 (0.42) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 | |
| SCHEMBL9537679 | 0.71 | ADORA3 (0.39) | KDM4EHTTSMN1; SMN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180352-B1 | BENZENE-FUSED HETEROCYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4767780-A | SUBSTITUTED 1,4-DIHYDRO-(1)-BENZOPYRANO(4,3-C)PYRAZOLES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-30 | — | — | US | disclosed |
| US-4675324-A | Substituted pyrazolo [4,3-c]pyridines and their use as uricosuric, diuretic and anti-hypertensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-23 | — | — | US | disclosed |
| EP-0180352-A2 | Benzene-fused heterocyclic compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |