Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574337 | 0.84 | RAB9A (0.66) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL7112031 | 0.80 | RAB9A (0.75) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL3530352 | 0.80 | THRB (0.54) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL11722234 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL6013323 | 0.77 | RAB9A (0.57) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL997166 | 0.74 | GAA (0.72) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL51830 | 0.74 | HCAR2 (0.70) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL7110355 | 0.74 | HPGD (0.67) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| Bromide SCHEMBL9033663 | 0.73 | GAA (0.71) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL5804219 | 0.73 | RAB9A (0.51) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480969-A4 | AMINO ACID ANALOG CCK ANTAGONISTS | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0480969-A1 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | disclosed |
| WO-1991000725-A2 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |