Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538389 | 0.83 | BDKRB1 (0.49) | HDAC1BDKRB1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9535579 | 0.81 | GAA (0.51) | HDAC1BDKRB1SMN1; SMN2GAAMAPT | |
| SCHEMBL9539537 | 0.80 | MAPK14 (0.47) | HDAC1ALDH1A1CES2CES1MAOB | |
| SCHEMBL29808947 | 0.77 | HDAC1 (0.73) | HDAC1SMN1; SMN2GAAHDAC3HDAC2 | |
| SCHEMBL15014104 | 0.77 | RAB9A (0.49) | HDAC1SMN1; SMN2GAAHDAC3HDAC2 | |
| SCHEMBL6106476 | 0.77 | HDAC1 (0.73) | HDAC1SMN1; SMN2GAAHDAC3HDAC2 | |
| SCHEMBL30148008 | 0.77 | SMN1; SMN2 (0.67) | HDAC1SMN1; SMN2GAAHDAC6MAPT | |
| SCHEMBL6694651 | 0.77 | SMN1; SMN2 (0.67) | HDAC1SMN1; SMN2GAAHDAC6MAPT | |
| SCHEMBL13291390 | 0.74 | CES2 (0.74) | L3MBTL1CES2CES1NPC1RAB9A | |
| SCHEMBL2055287 | 0.74 | HDAC1 (0.54) | HDAC1SMN1; SMN2GAAHDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |