SCHEMBL9536933

SCHEMBL9536933

NC(=O)N(O)C1CCc2cc(Oc3ccc(Cl)cc3)ccc21

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9203514 0.89 ALOX5 (0.46) ALOX5
SCHEMBL9597410 0.88 ALOX5 (0.41) ALOX5
SCHEMBL9597206 0.88 PPARD (0.43)
SCHEMBL9597053 0.88 ALOX5 (0.54) ALOX5
SCHEMBL9597496 0.87 ALOX5 (0.42) ALOX5
SCHEMBL9597113 0.86 PPARD (0.46)
SCHEMBL9535885 0.86 TRPM8 (0.42)
SCHEMBL9596948 0.83 PPARD (0.47) ALOX5
SCHEMBL9206933 0.83 ALOX5 (0.49) ALOX5
SCHEMBL9597708 0.83 PPARD (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5256789-A Antiinflammatory hydroxamic acids and N-hydroxyureas PFIZER INC. (US) 1993-10-26 US disclosed
EP-0525111-A1 ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS. PFIZER (US) 1993-02-03 EP disclosed
WO-1991016298-A1 ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS PFIZER INC (US) 1991-10-31 WO disclosed