Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597113 | 0.94 | PPARD (0.46) | — | |
| SCHEMBL9490649 | 0.93 | P2RX3 (0.49) | — | |
| SCHEMBL9597770 | 0.90 | ACHE (0.45) | ALOX5 | |
| SCHEMBL9206933 | 0.89 | ALOX5 (0.49) | ALOX5 | |
| SCHEMBL9597741 | 0.89 | PPARD (0.47) | — | |
| SCHEMBL9596948 | 0.89 | PPARD (0.47) | ALOX5 | |
| SCHEMBL9597410 | 0.89 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9597053 | 0.89 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9536933 | 0.89 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9597206 | 0.89 | PPARD (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525111-B1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER (US) | 1995-06-14 | — | — | EP | claimed |
| EP-0525111-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS. | PFIZER (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | claimed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | claimed |
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |