Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536702 | 0.79 | SMN1; SMN2 (0.39) | TSHRALDH1A1 | |
| SCHEMBL8950429 | 0.75 | ALDH1A1 (0.46) | CNR1CNR2TSHRGAAAGTR1 | |
| SCHEMBL14463376 | 0.74 | CNR1 (0.62) | CNR1CNR2TSHRGAAAGTR1 | |
| SCHEMBL14464974 | 0.74 | CNR1 (0.62) | CNR1CNR2TSHRGAAAGTR1 | |
| SCHEMBL9535573 | 0.73 | KMT2A (0.36) | ALDH1A1 | |
| SCHEMBL9687425 | 0.70 | TSHR (0.43) | CNR1CNR2TSHRGAAAGTR1 | |
| SCHEMBL9687433 | 0.70 | TSHR (0.43) | CNR1CNR2TSHRGAAAGTR1 | |
| SCHEMBL9687438 | 0.70 | TSHR (0.43) | CNR1CNR2TSHRGAAAGTR1 | |
| SCHEMBL5929382 | 0.70 | ALDH1A1 (0.37) | TSHRALDH1A1ATMALOX15 | |
| SCHEMBL11211107 | 0.70 | HTR2A (0.47) | TSHRGAAAGTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5091537-A | Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |