Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571183 | 0.79 | KMT2A (0.42) | KMT2APOLBPARP1ALDH1A1CDK5 | |
| SCHEMBL8575944 | 0.75 | KMT2A (0.46) | KMT2APOLBALDH1A1 | |
| SCHEMBL9537022 | 0.73 | CNR1 (0.46) | ALDH1A1 | |
| SCHEMBL3603694 | 0.69 | KMT2A (0.40) | KMT2APOLBALDH1A1 | |
| SCHEMBL9536702 | 0.68 | SMN1; SMN2 (0.39) | KMT2APOLBALDH1A1CDK5CDK5R1 | |
| SCHEMBL5451185 | 0.64 | KMT2A (0.39) | KMT2APOLBALDH1A1 | |
| SCHEMBL12718333 | 0.63 | HTR2C (0.43) | CDK5DYRK1ACDK5R1 | |
| SCHEMBL5929382 | 0.62 | ALDH1A1 (0.37) | KMT2APOLBALDH1A1 | |
| SCHEMBL6468219 | 0.61 | KMT2A (0.47) | KMT2APOLBALDH1A1 | |
| SCHEMBL6365121 | 0.61 | KMT2A (0.47) | KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5142065-A | Intermediates for herbicides, fungicides, miticides and insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |