Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537022 | 0.79 | CNR1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL8571183 | 0.73 | KMT2A (0.42) | ALDH1A1KMT2AMEN1POLBCDK5 | |
| SCHEMBL8950185 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1AADATKMT2AMEN1 | |
| SCHEMBL5929382 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1AADATKMT2AMEN1 | |
| SCHEMBL10760700 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8575944 | 0.69 | KMT2A (0.46) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9535573 | 0.68 | KMT2A (0.36) | ALDH1A1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL13879486 | 0.67 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL10377781 | 0.66 | HRH3 (0.43) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11886903 | 0.65 | KDM4E (0.37) | ALDH1A1KMT2AMEN1HPGDCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2111773-A | — | — | None | — | — | JP | disclosed |
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5142065-A | Intermediates for herbicides, fungicides, miticides and insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-5091537-A | Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| JP-H02111773-A | 3-ARYLPYRROLIDINE-2,4-DIONE (E) DERIVATIVE | BAYER AG | 1990-04-24 | — | — | JP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |