Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.56 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.56 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537682 | 0.86 | MAPT (0.60) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9538378 | 0.82 | USP7 (0.59) | MAPTMEN1KMT2APOLBPDE7A | |
| Acetic Acid SCHEMBL8213274 | 0.80 | MAPT (0.67) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9538024 | 0.80 | PDE7A (0.65) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9535501 | 0.80 | MAPT (0.56) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9534662 | 0.79 | MAPT (0.55) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9536992 | 0.79 | MAPT (0.51) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL18779398 | 0.79 | MEN1 (0.74) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9536565 | 0.79 | PDE7A (0.54) | MAPTMEN1KMT2APOLBPDE7A | |
| SCHEMBL9537140 | 0.77 | MAPT (0.57) | MAPTMEN1KMT2APOLBPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |