Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536481 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDLMNAGAA | |
| SCHEMBL9538024 | 0.80 | PDE7A (0.65) | MAPTALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL9537086 | 0.77 | MAPT (0.80) | MAPTALDH1A1HPGDGAAPOLB | |
| SCHEMBL9536557 | 0.75 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDLMNAGAA | |
| SCHEMBL9538378 | 0.74 | USP7 (0.59) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL9535501 | 0.72 | MAPT (0.56) | MAPTALDH1A1LMNAGAAPOLB | |
| SCHEMBL27273735 | 0.72 | PRNP (0.49) | MAPTALDH1A1HPGDLMNAGAA | |
| SCHEMBL9534662 | 0.71 | MAPT (0.55) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL5244464 | 0.71 | GSTP1 (0.63) | MAPTALDH1A1HPGDLMNAGAA | |
| SCHEMBL9536992 | 0.71 | MAPT (0.51) | MAPTALDH1A1LMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |