Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PDE7A | Q13946 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | USP7 | Q93009 | 2/20 | 0.56 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537086 | 0.86 | MAPT (0.80) | MAPTPDE7AKMT2APOLBBCL2L1 | |
| SCHEMBL9535431 | 0.84 | USP7 (0.60) | MAPTPDE7AKMT2AATMUSP7 | |
| SCHEMBL4963975 | 0.82 | PDE7A (0.82) | MAPTPDE7AKMT2APOLBBCL2L1 | |
| SCHEMBL9538378 | 0.80 | USP7 (0.59) | MAPTPDE7AKMT2AATMUSP7 | |
| SCHEMBL2962041 | 0.78 | PDE7A (0.65) | MAPTPDE7AKMT2AUSP7PADI4 | |
| SCHEMBL9536561 | 0.77 | MAPT (0.57) | MAPTPDE7AKMT2AUSP7PADI4 | |
| SCHEMBL18779398 | 0.77 | MEN1 (0.74) | MAPTPDE7AKMT2APOLBMEN1 | |
| SCHEMBL9536992 | 0.77 | MAPT (0.51) | MAPTPDE7AKMT2AATMUSP7 | |
| SCHEMBL16327556 | 0.77 | MAPT (0.78) | MAPTPDE7AKMT2APOLBBCL2L1 | |
| SCHEMBL1923978 | 0.77 | BCL2L1 (0.74) | MAPTPDE7AKMT2APOLBBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |