Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537079 | 0.79 | MAPT (0.43) | PDE7AMAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9537086 | 0.79 | MAPT (0.80) | PDE7AMAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9537100 | 0.78 | PDE7A (0.50) | PDE7AMAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL8099370 | 0.76 | PDE7A (0.67) | PDE7AMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9536540 | 0.75 | PDE7A (0.55) | PDE7AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9538378 | 0.75 | USP7 (0.59) | PDE7AMAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9536992 | 0.75 | MAPT (0.51) | PDE7AMAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9537682 | 0.74 | MAPT (0.60) | PDE7AMAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9535213 | 0.73 | PTGS2 (0.56) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9538024 | 0.73 | PDE7A (0.65) | PDE7AMAPTPOLBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |