Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 5/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538507 | 0.81 | PTGS2 (0.55) | ALDH1A1SMN1; SMN2NPSR1HPGDGAA | |
| SCHEMBL9536481 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PRNPRXFP1NPSR1 | |
| SCHEMBL9535010 | 0.78 | PTGS2 (0.54) | ALDH1A1SMN1; SMN2NPSR1HPGDMAPT | |
| SCHEMBL9539520 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL9537140 | 0.75 | MAPT (0.57) | ALDH1A1SMN1; SMN2PRNPRXFP1NPSR1 | |
| SCHEMBL9538064 | 0.74 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL9535213 | 0.73 | PTGS2 (0.56) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL9537700 | 0.73 | AKR1C3 (0.50) | ALDH1A1SMN1; SMN2RXFP1HPGDMAPT | |
| SCHEMBL9535435 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPSR1KDM4EHPGD | |
| SCHEMBL9538401 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019388-B | Process for preparing N-alkylsulfonamide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | CN | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |