Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754369 | 0.81 | NOTUM (0.48) | KDM4EALPLGAANOTUMCA12 | |
| SCHEMBL9534937 | 0.75 | KDM4E (0.50) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL30602735 | 0.74 | NOTUM (0.53) | KDM4EGAANOTUMPOLBCA12 | |
| SCHEMBL2116388 | 0.74 | CA12 (0.53) | KDM4EALPLGAATYMPPTPN1 | |
| SCHEMBL509972 | 0.74 | KDM4E (0.57) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL11736368 | 0.74 | KDM4E (0.61) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL8535240 | 0.73 | NOTUM (0.68) | KDM4ENOTUMCA12CA1CA9 | |
| SCHEMBL8570718 | 0.73 | KDM4E (0.51) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL2289477 | 0.72 | KDM4E (0.50) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL9754547 | 0.72 | MCL1 (0.55) | KDM4EALPLGAATYMPPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418853-B | Substituted naphthyridines-2-ketonic compound, preparation method, purposes and pharmaceutical composition | 北大方正集团有限公司 | 2016-09-07 | — | — | CN | disclosed |
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |