Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3749102 | 0.74 | KDM4E (0.54) | KDM4EMCL1PARP1 | |
| SCHEMBL9360263 | 0.74 | NPC1 (0.47) | KDM4E | |
| SCHEMBL509972 | 0.74 | KDM4E (0.57) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL9537201 | 0.73 | KDM4E (0.61) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL16664827 | 0.72 | MPO (0.53) | KDM4EGAAGSK3BCDK5CDK5R1 | |
| SCHEMBL31059216 | 0.69 | KDR (0.53) | KDM4EGSK3BPOLB | |
| SCHEMBL9534937 | 0.68 | KDM4E (0.50) | KDM4EALPLGAATYMPGSK3B | |
| SCHEMBL25302086 | 0.67 | ALDH1A1 (0.59) | KDM4EALPLGAAPTPN1POLB | |
| SCHEMBL29350007 | 0.67 | ALDH1A1 (0.59) | KDM4EALPLGAAPTPN1POLB | |
| SCHEMBL27953 | 0.67 | ALDH1A1 (0.59) | KDM4EALPLGAAPTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | claimed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | claimed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | claimed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | claimed |
| JP-10226646-A | — | — | None | — | — | JP | disclosed |
| JP-5155772-A | — | — | None | — | — | JP | disclosed |
| JP-10218772-A | — | — | None | — | — | JP | disclosed |
| JP-H10226646-A | THERAPEUTIC AGENT OF PARKINSONISM | TANABE SEIYAKU CO LTD | 1998-08-25 | — | — | JP | disclosed |
| JP-H10218772-A | PREVENTIVE AND THERAPEUTIC AGENT FOR HYPOBULIA AND LOWERING OF SPONTANEITY DUE TO CEREBROVASCULAR ACCIDENT OR DEPRESSION SYSTEM | TANABE SEIYAKU CO LTD | 1998-08-18 | — | — | JP | disclosed |
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| JP-H05155772-A | ANTIDEPRESSANT | TANABE SEIYAKU CO LTD | 1993-06-22 | — | — | JP | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |