Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535623 | 0.76 | PTGS2 (0.46) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL9534839 | 0.69 | HSD17B10 (0.49) | KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9535483 | 0.67 | IKBKB (0.52) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL19987117 | 0.67 | PIM1 (0.58) | KDM4EHSD17B10ALDH1A1ADORA2AJAK2 | |
| SCHEMBL9056918 | 0.66 | PTPN5 (0.48) | KDM4EHPGDCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL1722035 | 0.66 | NFKBIA (0.43) | KDM4EHPGDALDH1A1TDP1ADORA2A | |
| SCHEMBL11389842 | 0.66 | JAK2 (0.45) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL21254035 | 0.66 | NPC1 (0.54) | HPGDALDH1A1CYP1A2CYP3A4KCNH2 | |
| SCHEMBL2615262 | 0.65 | CTSS (0.60) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL12629284 | 0.65 | SLC1A3 (0.48) | CYP1A2CYP3A4ADORA2AADORA1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353902-B1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5127936-A | Substituted phenyltriazolopyrimidine herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1990012012-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0353902-A1 | Substituted phenyltriazolopyrimidine herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |