Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.64 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244 | 0.88 | SOS1 (0.64) | SOS1ALDH1A1HSD17B10TDP1HTT | |
| SCHEMBL9536733 | 0.88 | SOS1 (0.64) | SOS1ALDH1A1HSD17B10TDP1HTT | |
| SCHEMBL9822529 | 0.86 | ALDH1A1 (0.60) | SRD5A2STSALDH1A1HSD17B10TDP1 | |
| SCHEMBL9536469 | 0.84 | SRD5A2 (0.88) | SRD5A2PARP10POLBERCC5FEN1 | |
| SCHEMBL235530 | 0.84 | SRD5A2 (0.88) | SRD5A2PARP10POLBERCC5FEN1 | |
| SCHEMBL2866068 | 0.84 | SRD5A2 (0.88) | SRD5A2PARP10POLBERCC5FEN1 | |
| SCHEMBL1082112 | 0.84 | SRD5A2 (0.88) | SRD5A2PARP10POLBERCC5FEN1 | |
| SCHEMBL13599782 | 0.84 | SRD5A2 (0.88) | SRD5A2PARP10POLBERCC5FEN1 | |
| SCHEMBL7892614 | 0.82 | SOS1 (0.58) | SOS1BCL2L1MCL1ALDH1A1HSD17B10 | |
| SCHEMBL22415445 | 0.82 | SRD5A2 (0.84) | SRD5A2PARP10POLBSTSERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178183-B1 | PREPARATION OF AROMATIC KETONE-SULFONE COPOLYMERS | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1993-01-20 | — | — | EP | disclosed |
| US-4593086-A | From carboxylic acid halide and aromatic dicarboxylic acid dihalide | RAYCHEM CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0178183-A2 | Preparation of aromatic ketone-sulfone copolymers | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |