SCHEMBL31244

SCHEMBL31244

O=S(=O)(Cl)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.64
ALDH1A1 P00352 2/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
LMNA P02545 4/20 0.58
HTT P42858 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
PGR P06401 6/20 0.53
LTA4H P09960 1/20 0.52
TSHR P16473 1/20 0.52
MMP1 P03956 2/20 0.51
MMP3 P08254 2/20 0.51
MMP8 P22894 2/20 0.51
MMP13 P45452 1/20 0.51
KDM4E B2RXH2 1/20 0.51
FFAR1 O14842 2/20 0.49
MMP2 P08253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9536733 1.00 SOS1 (0.64) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL7892614 0.94 SOS1 (0.58) SOS1ALDH1A1HSD17B10TDP1LMNA
Diphenylether SCHEMBL4640253 0.92 PGR (0.64) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL433497 0.91 HTT (0.58) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL9720036 0.91 HTT (0.58) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL9539212 0.90 ALDH1A1 (0.56) SOS1ALDH1A1HSD17B10TDP1LMNA
Anisole SCHEMBL3037045 0.89 LTA4H (0.62) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL1304736 0.88 HTT (0.53) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL9537305 0.88 SRD5A2 (0.64) SOS1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL12111317 0.87 ALDH1A1 (0.52) SOS1ALDH1A1HSD17B10TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2385831-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT The UAB Research Foundation (US) 2011-11-16 EP claimed
US-20110254866-A1 INFORMATION PROCESSING APPARATUS, METHOD AND PROGRAM THEREFORE SONY CORPORATION (JP) 2011-10-20 US claimed
WO-2010123591-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT THE UAB RESEARCH FOUNDATION (US) 2010-10-28 WO claimed
EP-0178183-B1 PREPARATION OF AROMATIC KETONE-SULFONE COPOLYMERS RAYCHEM CORPORATION (a Delaware corporation) (US) 1993-01-20 EP claimed
US-4593086-A From carboxylic acid halide and aromatic dicarboxylic acid dihalide RAYCHEM CORPORATION (US) 1986-06-03 US claimed
EP-0178183-A2 Preparation of aromatic ketone-sulfone copolymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP claimed
JP-5310683-A None JP disclosed
US-12595243-B2 Modulators of extracellular signal-regulated kinase GEN1E LIFESCIENCES INC. (US) 2026-04-07 US disclosed
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2026-03-10 US disclosed
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function Lee Moffitt Cancer Center and Research Institute, Inc. (US) 2026-03-03 US disclosed
US-12479821-B2 Quinoline compound and use thereof MBD Co., Ltd. (KR) 2025-11-25 US disclosed
US-20250353826-A1 INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE GEN1E LIFESCIENCES INC (US) 2025-11-20 US disclosed
US-12404259-B2 Inhibitors of extracellular signal-regulated kinase GEN1E LIFESCIENCES INC. (US) 2025-09-02 US disclosed
EP-0019126-A2 Flame resistant polycarbonate composition with high resistance against deformation by heat; their preparation and their use BAYER AG (DE) 1980-11-26 EP disclosed
US-4200465-A Antistatic light-sensitive silver halide photographic element KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-04-29 US disclosed
US-4051303-A RECORDING SHEET FUJI PHOTO FILM CO., LTD. (JA) 1977-09-27 US disclosed
US-4041051-A 1-AMINO-4-HYDROXY-2-(P-METHOXY OR ETHOXY-BENZENESULFONYLOXY)-ANTHRAQUINONE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-09 US disclosed
US-4021245-A GELATION DERIVATIVE, SILICIC ACID ANHYDRIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed
US-3983300-A POLYAROMATIC SULFONE IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1976-09-28 US disclosed
US-3944502-A Process for preparing microcapsules containing hydrophobic oil drops FUJI PHOTO FILM CO., LTD. (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479821-B2 Quinoline compound and use thereof CYP4A11, CYP7A1, CYP4B1 SOS1 3784/4885ALDH1A1 647/4885HSD17B10 65/4885
US-20250353826-A1 INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE MAP3K20, MAP3K6, MAP3K19 SOS1 742/4885ALDH1A1 3878/4885HSD17B10 4261/4885
US-12404259-B2 Inhibitors of extracellular signal-regulated kinase MAP3K20, MAP3K6, MAP3K19 SOS1 742/4885ALDH1A1 3878/4885HSD17B10 4261/4885
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer CKS2, CSNK2A3, CSNK1A1L SOS1 4012/4885ALDH1A1 1571/4885HSD17B10 1111/4885
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function CRBN, CD4, ICOS SOS1 2894/4885ALDH1A1 2373/4885HSD17B10 4424/4885
US-12595243-B2 Modulators of extracellular signal-regulated kinase CDC42BPG, GRK3, ERBB2 SOS1 783/4885ALDH1A1 2876/4885HSD17B10 2235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.