Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536336 | 0.84 | SCN9A (0.54) | LMNASMN1; SMN2TSHRMAPTHTT | |
| SCHEMBL27936754 | 0.80 | HSD17B10 (0.59) | LMNASMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL5243618 | 0.80 | HSD17B10 (0.59) | LMNASMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL9533615 | 0.80 | HSD17B10 (0.59) | LMNASMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL9533388 | 0.77 | TSHR (0.51) | LMNATSHRMAPTHTTALDH1A1 | |
| SCHEMBL9535039 | 0.77 | KMT2A (0.67) | LMNASMN1; SMN2TSHRMAPTHTT | |
| SCHEMBL9533601 | 0.77 | MAPT (0.51) | LMNATSHRMAPTHTTALDH1A1 | |
| SCHEMBL9532664 | 0.74 | HSD17B10 (0.53) | LMNASMN1; SMN2TSHRMAPTHTT | |
| SCHEMBL9534238 | 0.74 | POLB (0.45) | SMN1; SMN2TSHRMAPTHTTKMT2A | |
| SCHEMBL9535356 | 0.74 | HSD17B10 (0.52) | LMNASMN1; SMN2TSHRMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |