Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534238 | 0.83 | POLB (0.45) | TSHRHTTMAPTNPSR1KDM4E | |
| SCHEMBL9535755 | 0.80 | ALDH1A1 (0.52) | MAPTALDH1A1GAACYP1A2CYP2C19 | |
| SCHEMBL9533884 | 0.79 | KMT2A (0.59) | TSHRHTTNPC1MAPTRXFP1 | |
| SCHEMBL9533937 | 0.78 | ALDH1A1 (0.50) | HTTMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9536170 | 0.78 | MAPT (0.52) | TSHRMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9537484 | 0.77 | LMNA (0.52) | TSHRHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL5242546 | 0.77 | KMT2A (0.56) | TSHRHTTGAAKMT2AMEN1 | |
| SCHEMBL27495331 | 0.76 | KMT2A (0.55) | TSHRHTTALDH1A1GAAKMT2A | |
| SCHEMBL9533918 | 0.75 | MAPT (0.64) | HTTNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9535701 | 0.74 | KMT2A (0.54) | TSHRHTTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |