Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483549 | 0.87 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9311576 | 0.76 | JAK2 (0.45) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11161401 | 0.75 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27469363 | 0.75 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9537505 | 0.75 | SLC9A1 (0.42) | ALDH1A1SMN1; SMN2BCAT2ATRTP53 | |
| SCHEMBL27472002 | 0.73 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2575446 | 0.73 | CA1 (0.49) | ALDH1A1KDM4ESMN1; SMN2GAABCAT2 | |
| SCHEMBL30752023 | 0.73 | CA1 (0.49) | ALDH1A1KDM4ESMN1; SMN2GAABCAT2 | |
| SCHEMBL9311245 | 0.71 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9537879 | 0.71 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |