Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805550 | 0.78 | RAB9A (0.49) | PIN1ALDH1A1TRPM8RAB9AXBP1 | |
| SCHEMBL18192240 | 0.71 | HTT (0.44) | PIN1TAS1R3TAS1R1ALDH1A1TRPM8 | |
| SCHEMBL9200502 | 0.70 | ALDH1A1 (0.46) | PIN1TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL1665427 | 0.70 | TRPM8 (0.49) | PIN1ALDH1A1TSHRTRPM8RAB9A | |
| SCHEMBL28300301 | 0.69 | TRPM8 (0.51) | PIN1ALDH1A1TSHRTRPM8RAB9A | |
| SCHEMBL28224648 | 0.69 | TRPM8 (0.51) | PIN1ALDH1A1TSHRTRPM8RAB9A | |
| SCHEMBL193593 | 0.69 | RAB9A (0.58) | PIN1ALDH1A1TRPM8RAB9AXBP1 | |
| SCHEMBL193594 | 0.69 | RAB9A (0.58) | PIN1ALDH1A1TRPM8RAB9AXBP1 | |
| SCHEMBL192338 | 0.66 | RAB9A (0.48) | PIN1ALDH1A1TRPM8RAB9AXBP1 | |
| SCHEMBL3418519 | 0.66 | TRPM8 (0.54) | PIN1ALDH1A1TRPM8RAB9AXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |