Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656377 | 0.89 | KMT2A (0.34) | ALDH1A1CYP1A2L3MBTL1LMNANPC1 | |
| SCHEMBL9782419 | 0.78 | PTGS2 (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C9TP53 | |
| SCHEMBL2457562 | 0.72 | KMT2A (0.47) | ALDH1A1CYP1A2LMNANPC1RAB9A | |
| SCHEMBL2457565 | 0.72 | KMT2A (0.47) | ALDH1A1CYP1A2LMNANPC1RAB9A | |
| SCHEMBL6505461 | 0.71 | NR1H2 (0.41) | ALDH1A1CYP1A2L3MBTL1LMNAFGFR1 | |
| SCHEMBL2839493 | 0.71 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP3A4CYP2C9ATM | |
| Bromide SCHEMBL27863912 | 0.69 | NR1H2 (0.39) | ALDH1A1CYP1A2L3MBTL1LMNAFGFR1 | |
| SCHEMBL5543150 | 0.69 | CHRM5 (0.42) | CYP1A2CYP2C9MAPTNPC1MEN1 | |
| SCHEMBL5540341 | 0.69 | NFE2L2 (0.46) | CYP1A2CYP3A4FGFR1NPC1RAB9A | |
| SCHEMBL291507 | 0.69 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP3A4TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564960-A1 | Imidazopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | disclosed |