Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539520 | 0.82 | ALDH1A1 (0.45) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9535010 | 0.80 | PTGS2 (0.54) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9538064 | 0.80 | ALDH1A1 (0.47) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2SLC22A12 | |
| SCHEMBL9538031 | 0.78 | MAPT (0.50) | AKR1C3AKR1C2ALDH1A1HPGDKMT2A | |
| SCHEMBL9535435 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDPTGS2KMT2A | |
| SCHEMBL9536230 | 0.76 | PTGS2 (0.55) | ALDH1A1SMN1; SMN2PLA2G7HPGDPTGS2 | |
| SCHEMBL9538507 | 0.75 | PTGS2 (0.55) | ALDH1A1SMN1; SMN2HPGDPTGS2KMT2A | |
| SCHEMBL9868559 | 0.75 | PTGS2 (0.48) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9535213 | 0.75 | PTGS2 (0.56) | ALDH1A1SMN1; SMN2HPGDPTGS2KMT2A | |
| SCHEMBL9534662 | 0.74 | MAPT (0.55) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |