Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538401 | 0.87 | ALDH1A1 (0.44) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9539520 | 0.83 | ALDH1A1 (0.45) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9538507 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9538064 | 0.81 | ALDH1A1 (0.47) | PTGS1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL9535213 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9537700 | 0.80 | AKR1C3 (0.50) | PTGS2ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL28393642 | 0.80 | PTGS2 (0.59) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9535435 | 0.80 | ALDH1A1 (0.43) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9536557 | 0.78 | ALDH1A1 (0.40) | PTGS2PTGS1ALDH1A1HPGDMAPT | |
| SCHEMBL9868559 | 0.78 | PTGS2 (0.48) | PTGS2PTGS1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |