Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758569 | 0.83 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL9298473 | 0.79 | TRPA1 (0.37) | — | |
| SCHEMBL8965119 | 0.79 | TRPA1 (0.37) | — | |
| SCHEMBL7825330 | 0.79 | TRPA1 (0.37) | — | |
| SCHEMBL9297323 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL6182661 | 0.74 | SLC6A4 (0.33) | ALOX5 | |
| SCHEMBL6491522 | 0.73 | CYP19A1 (0.41) | — | |
| SCHEMBL6093810 | 0.73 | CA1 (0.39) | — | |
| SCHEMBL6092003 | 0.71 | — | — | |
| SCHEMBL7697891 | 0.70 | ALOX5 (0.43) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386778-B1 | BIPHENYL DERIVATIVES | TANABE SEIYAKU CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5169861-A | Therapeutic or prophylactic agent for hepatic diseases | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-08 | — | — | US | disclosed |
| US-5066669-A | Hepatitis, liver disorders | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0386778-A1 | Biphenyl derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |