Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536239 | 0.84 | SMN1; SMN2 (0.35) | PDE4BPDE4DACHEPOLBPDK1 | |
| SCHEMBL9536988 | 0.84 | SMN1; SMN2 (0.37) | PDE4BPDE4DACHEPOLB | |
| SCHEMBL10400129 | 0.82 | MAPT (0.44) | PDE4BPDE4DMAPTACHEPOLB | |
| SCHEMBL10401077 | 0.82 | PDE4B (0.41) | PDE4BPDE4DMAPTACHE | |
| SCHEMBL10401012 | 0.79 | KMT2A (0.35) | PDE4BPDE4DACHEPDK1PDK2 | |
| SCHEMBL10400747 | 0.79 | KMT2A (0.33) | PDE4BPDE4DACHEPDK1PDK2 | |
| SCHEMBL10401013 | 0.78 | PDE4B (0.35) | PDE4BPDE4DPOLB | |
| SCHEMBL9539862 | 0.76 | ALDH1A1 (0.35) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL10517413 | 0.74 | ALDH1A1 (0.34) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL10400826 | 0.74 | F2 (0.34) | MAPTACHEPOLBPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |