Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400826 | 0.87 | F2 (0.34) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL10517413 | 0.86 | ALDH1A1 (0.34) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL10400918 | 0.83 | ALDH1A1 (0.35) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10400124 | 0.82 | LMNA (0.34) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10400122 | 0.81 | TAS1R3 (0.34) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL9536988 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2P2RX1MEN1KMT2A | |
| SCHEMBL9536239 | 0.78 | SMN1; SMN2 (0.35) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL9535151 | 0.77 | LMNA (0.34) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10458605 | 0.77 | KMT2A (0.40) | ALDH1A1HTTATMSMN1; SMN2MEN1 | |
| SCHEMBL10400150 | 0.77 | MAPK14 (0.41) | PDK1PDK2PDK3PDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |