Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535948 | 0.86 | HDAC6 (0.37) | CTSKHDAC6CA14HDAC1HDAC2 | |
| SCHEMBL21025722 | 0.80 | ALDH1A1 (0.38) | CTSKHDAC6MEN1GAAKMT2A | |
| SCHEMBL12039797 | 0.78 | CA14 (0.45) | CTSKHDAC6MEN1GAAKMT2A | |
| SCHEMBL22154645 | 0.77 | CA14 (0.36) | CTSKHDAC6CA14HDAC1HDAC2 | |
| SCHEMBL16941095 | 0.77 | CTSK (0.39) | CTSKHDAC6MEN1GAAKMT2A | |
| SCHEMBL9535145 | 0.76 | HDAC6 (0.35) | CTSKHDAC6CA14HDAC1HDAC2 | |
| SCHEMBL1193477 | 0.76 | HDAC6 (0.35) | CTSKHDAC6CA14HDAC1HDAC2 | |
| SCHEMBL2836031 | 0.76 | HDAC6 (0.38) | CTSKHDAC6CA14HDAC1HDAC2 | |
| SCHEMBL24569367 | 0.76 | HDAC6 (0.31) | HDAC6 | |
| SCHEMBL24569698 | 0.76 | HDAC6 (0.31) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |