Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24569367 | 1.00 | HDAC6 (0.31) | HDAC6 | |
| SCHEMBL9535948 | 0.82 | HDAC6 (0.37) | HDAC6 | |
| SCHEMBL9537778 | 0.76 | CTSK (0.34) | HDAC6 | |
| SCHEMBL24569342 | 0.74 | HDAC6 (0.36) | HDAC6 | |
| SCHEMBL2836031 | 0.72 | HDAC6 (0.38) | HDAC6 | |
| SCHEMBL23221887 | 0.70 | HDAC6 (0.32) | HDAC6 | |
| SCHEMBL20670458 | 0.70 | NFKB1 (0.34) | HDAC6 | |
| SCHEMBL22154645 | 0.67 | CA14 (0.36) | HDAC6 | |
| SCHEMBL9535145 | 0.66 | HDAC6 (0.35) | HDAC6 | |
| SCHEMBL17039171 | 0.66 | HDAC6 (0.33) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140769-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |