Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 10/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455699 | 1.00 | OPRK1 (0.47) | OPRK1OPRD1OPRM1CYP2D6TSHR | |
| SCHEMBL8827729 | 1.00 | OPRK1 (0.47) | OPRK1OPRD1OPRM1CYP2D6TSHR | |
| Salicylic Acid SCHEMBL9541177 | 0.87 | BCHE (0.43) | OPRK1OPRD1OPRM1CYP2D6TSHR | |
| SCHEMBL9539147 | 0.87 | OPRM1 (0.44) | OPRK1OPRD1OPRM1CYP2D6KDM4E | |
| SCHEMBL9537701 | 0.86 | OPRM1 (0.47) | OPRK1OPRD1OPRM1CYP2D6KDM4E | |
| SCHEMBL2457359 | 0.85 | OPRD1 (0.42) | OPRK1OPRD1OPRM1CYP2D6TSHR | |
| SCHEMBL2457355 | 0.85 | OPRD1 (0.42) | OPRK1OPRD1OPRM1CYP2D6TSHR | |
| SCHEMBL9538266 | 0.85 | OPRD1 (0.42) | OPRK1OPRD1OPRM1CYP2D6TSHR | |
| SCHEMBL2455192 | 0.83 | BCHE (0.48) | CYP2D6TSHRKDM4ETP53ALOX15 | |
| SCHEMBL2455194 | 0.83 | BCHE (0.48) | CYP2D6TSHRKDM4ETP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |