Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.62 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149663 | 0.81 | FDPS (0.65) | MCL1ACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL10591476 | 0.81 | FLT3 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9534725 | 0.80 | KDM4E (0.66) | MCL1ACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL9534579 | 0.80 | MCL1 (0.78) | MCL1ACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL10893692 | 0.80 | MCL1 (0.56) | MCL1ACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL25125819 | 0.79 | ALDH1A1 (0.59) | MCL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29788086 | 0.79 | CHEK1 (0.60) | MCL1ACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL504872 | 0.79 | CHEK1 (0.60) | MCL1ACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL29900122 | 0.79 | ALDH1A1 (0.59) | MCL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2770512 | 0.78 | ALDH1A1 (0.67) | MCL1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |