Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13133475 | 0.93 | HPGD (0.55) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL10024697 | 0.93 | ALDH1A1 (0.55) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL6927546 | 0.92 | GAA (0.65) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL95195 | 0.91 | KDM4E (0.54) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL13539013 | 0.89 | KDM4E (0.51) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL13539011 | 0.86 | CFD (0.60) | HPGDKDM4EMAPTALDH1A1SAE1 | |
| SCHEMBL15831652 | 0.85 | ALDH1A1 (0.56) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL13539015 | 0.85 | KDM4E (0.56) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL168810 | 0.82 | HPGD (0.45) | HPGDKDM4EMAPTALDH1A1GAA | |
| SCHEMBL14415935 | 0.82 | HPGD (0.57) | HPGDKDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035884-B2 | Polysiloxane-polycarbonate block cocondensates with improved rheological properties | COVESTRO DEUTSCHLAND AG (DE) | 2018-07-31 | — | — | US | disclosed |
| US-9969879-B2 | Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties | COVESTRO DEUTSCHLAND AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20180079862-A1 | BLOCK CO-CONDENSATES OF POLYSILOXANES AND DIHYDROXYDIPHENYLCYCLOALKANE-BASED N (CO)POLYCARBONATES | COVESTRO DEUTSCHLAND AG (DE) | 2018-03-22 | — | — | US | disclosed |
| US-20180009986-A1 | FLAME-RETARDANT MOLDING COMPOUNDS CONTAINING SILOXANE-CONTAINING POLYCARBONATE BLOCK CO-CONDENSATE | COVESTRO DEUTSCHLAND AG (DE) | 2018-01-11 | — | — | US | disclosed |
| US-20170369707-A1 | FLAME-RETARDANT, GLASS FIBER-CONTAINING MOLDING COMPOUNDS CONTAINING SILOXANE-CONTAINING POLYCARBONATE BLOCK CO-CONDENSATE | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9845379-B2 | Polysiloxane-polycarbonate block cocondensates | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9845378-B2 | Process for preparing polysiloxane-polycarbonate block cocondensates | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9828462-B2 | Preparation of siloxane-containing block copolycarbonates by means of reactive extrusion | COVESTRO DEUTSCHLAND AG (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20170233571-A1 | Copolycarbonate Compositions with Branch Structures and Cyclic Oligomers and Improved Rheological Properties | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170226340-A1 | Copolycarbonate Compositions with Branch Structures and Linear Oligomers and Improved Rheological Properties | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20120059098-A1 | FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| US-8110649-B2 | Polycarbonates comprising cyclic oligomers and having an improved flow behavior | BAYER MATERIALSCIENCE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-20110245388-A1 | POLYCARBONATE RESIN COMPOSITION AND FORMED PRODUCT THEREOF | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110040066-A1 | POLYCARBONATES HAVING REARRANGEMENT STRUCTURES, CYCLIC AND LINEAR OLIGOMERS AND ALSO FLOW BEHAVIOR | BAYER MATERIALSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110003945-A1 | POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR | BAYER MATERIALSCIENCE AG | 2011-01-06 | — | — | US | disclosed |
| US-20100244303-A1 | PRODUCTION METHOD OF AROMATIC POLYCARBONATE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100069543-A1 | FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSTION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7511114-B2 | Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7271235-B2 | Branched aromatic polycarbonate and its production method | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-09-18 | — | — | US | disclosed |
| US-20070129471-A1 | Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245388-A1 | POLYCARBONATE RESIN COMPOSITION AND FORMED PRODUCT THEREOF | PTCD3, PSMC2, COPE | HPGD 4113/4885KDM4E 837/4885MAPT 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.