SCHEMBL10024697

SCHEMBL10024697

COC(=O)c1cc(Cc2ccc(OC)cc2)ccc1Oc1ccc(Cc2ccc(OC)cc2)cc1C(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 3/20 0.55
HPGD P15428 3/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
HSD17B10 Q99714 1/20 0.55
SAE1 Q9UBE0 1/20 0.51
UBA2 Q9UBT2 1/20 0.51
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
LTA4H P09960 1/20 0.45
LMNA P02545 2/20 0.44
HTT P42858 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95195 0.96 KDM4E (0.54) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL95380 0.93 HPGD (0.56) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL13133475 0.88 HPGD (0.55) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL13539013 0.87 KDM4E (0.51) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL6927546 0.84 GAA (0.65) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL15831652 0.84 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL13539015 0.84 KDM4E (0.56) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL1108684 0.82 KDM4E (0.58) ALDH1A1KDM4ESAE1UBA2KMT2A
SCHEMBL14795270 0.79 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL13539011 0.79 CFD (0.60) ALDH1A1KDM4EHPGDMAPTSAE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10035884-B2 Polysiloxane-polycarbonate block cocondensates with improved rheological properties COVESTRO DEUTSCHLAND AG (DE) 2018-07-31 US disclosed
US-9969879-B2 Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties COVESTRO DEUTSCHLAND AG (DE) 2018-05-15 US disclosed
US-20180079862-A1 BLOCK CO-CONDENSATES OF POLYSILOXANES AND DIHYDROXYDIPHENYLCYCLOALKANE-BASED N (CO)POLYCARBONATES COVESTRO DEUTSCHLAND AG (DE) 2018-03-22 US disclosed
US-20180009986-A1 FLAME-RETARDANT MOLDING COMPOUNDS CONTAINING SILOXANE-CONTAINING POLYCARBONATE BLOCK CO-CONDENSATE COVESTRO DEUTSCHLAND AG (DE) 2018-01-11 US disclosed
US-20170369707-A1 FLAME-RETARDANT, GLASS FIBER-CONTAINING MOLDING COMPOUNDS CONTAINING SILOXANE-CONTAINING POLYCARBONATE BLOCK CO-CONDENSATE COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
US-9845379-B2 Polysiloxane-polycarbonate block cocondensates COVESTRO DEUTSCHLAND AG (DE) 2017-12-19 US disclosed
US-9845378-B2 Process for preparing polysiloxane-polycarbonate block cocondensates COVESTRO DEUTSCHLAND AG (DE) 2017-12-19 US disclosed
US-9828462-B2 Preparation of siloxane-containing block copolycarbonates by means of reactive extrusion COVESTRO DEUTSCHLAND AG (DE) 2017-11-28 US disclosed
US-20170233571-A1 Copolycarbonate Compositions with Branch Structures and Cyclic Oligomers and Improved Rheological Properties COVESTRO DEUTSCHLAND AG (DE) 2017-08-17 US disclosed
US-20170226340-A1 Copolycarbonate Compositions with Branch Structures and Linear Oligomers and Improved Rheological Properties COVESTRO DEUTSCHLAND AG (DE) 2017-08-10 US disclosed
US-8715552-B2 Production method of aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 2014-05-06 US disclosed
US-8158745-B2 Polycarbonates having rearrangement structures, cyclic and linear oligomers and also flow behavior BAYER MATERIALSCIENCE AG (DE) 2012-04-17 US disclosed
US-8110649-B2 Polycarbonates comprising cyclic oligomers and having an improved flow behavior BAYER MATERIALSCIENCE AG (DE) 2012-02-07 US disclosed
US-20110040066-A1 POLYCARBONATES HAVING REARRANGEMENT STRUCTURES, CYCLIC AND LINEAR OLIGOMERS AND ALSO FLOW BEHAVIOR BAYER MATERIALSCIENCE AG (DE) 2011-02-17 US disclosed
US-20110003945-A1 POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR BAYER MATERIALSCIENCE AG 2011-01-06 US disclosed
US-20100244303-A1 PRODUCTION METHOD OF AROMATIC POLYCARBONATE MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-30 US disclosed
US-20100069543-A1 FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSTION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2010-03-18 US disclosed
US-7511114-B2 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-31 US disclosed
US-7271235-B2 Branched aromatic polycarbonate and its production method MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-18 US disclosed
US-20070129471-A1 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-07 US disclosed