Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26246202 | 0.94 | HPGD (0.42) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL9694657 | 0.93 | ALDH1A1 (0.44) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL28364585 | 0.87 | HPGD (0.49) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL23668701 | 0.81 | HPGD (0.47) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL23691384 | 0.81 | HPGD (0.47) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL23668692 | 0.81 | HPGD (0.47) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL23668706 | 0.81 | HPGD (0.47) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL22235702 | 0.80 | HPGD (0.44) | HPGDHTTLMNASMN1; SMN2POLB | |
| SCHEMBL16359263 | 0.80 | HPGD (0.44) | HPGDHTTLMNASMN1; SMN2POLB | |
| Methylene Chloride SCHEMBL7294170 | 0.80 | ALDH1A1 (0.49) | HPGDHTTLMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540606-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP plc (GB) | 1993-05-12 | — | — | EP | disclosed |