Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541062 | 0.79 | STING1 (0.36) | KMT2ATSHRALDH1A1STING1POLB | |
| SCHEMBL9538461 | 0.77 | STING1 (0.47) | L3MBTL1TSHRSTING1 | |
| SCHEMBL9540466 | 0.77 | PPARG (0.40) | TDP1TSHRSTING1POLB | |
| SCHEMBL9537166 | 0.76 | STING1 (0.33) | KMT2ATSHRALDH1A1STING1 | |
| SCHEMBL9540660 | 0.74 | CYP3A4 (0.39) | TSHRSTING1 | |
| SCHEMBL9538537 | 0.73 | STING1 (0.43) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL9538258 | 0.72 | CYP2A6 (0.44) | KMT2AMAPK1TSHRALDH1A1STING1 | |
| SCHEMBL9541014 | 0.72 | ALDH1A1 (0.36) | TDP1MEN1KMT2AMAPK1TSHR | |
| SCHEMBL9541789 | 0.70 | TSHR (0.40) | KMT2ATSHRSTING1 | |
| SCHEMBL9540989 | 0.69 | STING1 (0.56) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005033-A1 | BENZO[b]THIOPHENE DERIVATES, PROCESS FOR PRODUCING THE SAME AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |