Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295552 | 0.89 | ALDH1A1 (0.57) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL12482627 | 0.85 | ALDH1A1 (0.53) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL27933652 | 0.77 | ALDH1A1 (0.54) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9463830 | 0.77 | GAA (0.46) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL12190874 | 0.76 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9463905 | 0.76 | HPGD (0.50) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL295187 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9463750 | 0.76 | ADRB2 (0.51) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9935576 | 0.75 | ALDH1A1 (0.59) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9463824 | 0.74 | ADRB2 (0.52) | ALDH1A1ADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | claimed |
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |