⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419675 | 0.80 | — | — | |
| SCHEMBL3170029 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL4924587 | 0.75 | — | — | |
| SCHEMBL1827552 | 0.75 | — | — | |
| SCHEMBL2411834 | 0.73 | — | — | |
| SCHEMBL3127463 | 0.72 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL7217104 | 0.71 | GBA1 (0.36) | — | |
| SCHEMBL6039653 | 0.70 | — | — | |
| SCHEMBL1754884 | 0.69 | NOS1 (0.33) | — | |
| SCHEMBL4918129 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |