Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534093 | 0.80 | ADRB3 (0.41) | PTGS2ADRB3PLA2G7TRPV1 | |
| SCHEMBL9537176 | 0.79 | PTGS2 (0.54) | PTGS2ADRB3 | |
| SCHEMBL9656960 | 0.79 | PTGS2 (0.54) | PTGS2ADRB3 | |
| SCHEMBL9535652 | 0.78 | PTGS2 (0.54) | PTGS2PLA2G7 | |
| SCHEMBL9539469 | 0.77 | PTGS2 (0.53) | PTGS2PLA2G7 | |
| SCHEMBL10626704 | 0.77 | PTGS2 (0.56) | PTGS2PLA2G7 | |
| SCHEMBL9534404 | 0.76 | PTGS2 (0.55) | PTGS2PLA2G7 | |
| SCHEMBL9534684 | 0.75 | PTGS2 (0.54) | PTGS2PLA2G7 | |
| SCHEMBL9540036 | 0.75 | PTGS2 (0.48) | PTGS2PLA2G7 | |
| SCHEMBL5676138 | 0.74 | TRPV1 (0.51) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |