Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535652 | 0.87 | PTGS2 (0.54) | PTGS2PLA2G7GAANPC1RAB9A | |
| SCHEMBL9539469 | 0.86 | PTGS2 (0.53) | PTGS2MAPK14PLA2G7CYP1A2CYP3A4 | |
| SCHEMBL9657068 | 0.80 | PTGS2 (0.53) | PTGS2MAPK14PLA2G7CYP1A2CYP3A4 | |
| SCHEMBL9537146 | 0.80 | PTGS2 (0.53) | PTGS2MAPK14PLA2G7CYP1A2CYP3A4 | |
| SCHEMBL9540036 | 0.79 | PTGS2 (0.48) | PTGS2MAPK14PLA2G7CYP1A2CYP3A4 | |
| SCHEMBL9536533 | 0.77 | ALDH1A1 (0.47) | MAPK14CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL9538416 | 0.76 | PTGS2 (0.53) | PTGS2PLA2G7 | |
| SCHEMBL10626704 | 0.76 | PTGS2 (0.56) | PTGS2PLA2G7LMNAACLY | |
| SCHEMBL9534684 | 0.74 | PTGS2 (0.54) | PTGS2PLA2G7ALDH1A1LMNA | |
| SCHEMBL9538281 | 0.74 | CA1 (0.44) | PTGS2GAANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |