Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813764 | 0.85 | CHRNA7 (0.41) | CHRNA7CYP1A2CYP2C9MEN1LMNA | |
| SCHEMBL5298667 | 0.81 | CHRNA7 (0.38) | CHRNA7CYP1A2CYP2C9LMNACYP2D6 | |
| Iodide SCHEMBL11575949 | 0.79 | CHRNA7 (0.37) | CHRNA7CYP1A2CYP2C9MEN1LMNA | |
| SCHEMBL5944519 | 0.79 | CHRNA7 (0.37) | CHRNA7CYP1A2CYP2C9LMNACYP2D6 | |
| Iodide SCHEMBL11574865 | 0.78 | APOBEC3A (0.40) | CHRNA7CYP1A2CYP2C9MEN1LMNA | |
| SCHEMBL10861780 | 0.77 | ORAI1 (0.33) | ORAI1ORAI2ORAI3TRPV6OPRM1 | |
| SCHEMBL4907271 | 0.76 | ORAI1 (0.40) | ORAI1ORAI2ORAI3TRPV6OPRM1 | |
| SCHEMBL15293602 | 0.76 | CYP1A2 (0.56) | CHRNA7ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL7973710 | 0.72 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL3175095 | 0.68 | MAOB (0.40) | SIGMAR1GBA1HTR2CHRH1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920113-A1 | SYNTHESIS OF MSE-FRAMEWORK TYPE MOLECULAR SIEVES | ExxonMobil Research and Engineering Company (US) | 2015-09-23 | — | — | EP | disclosed |
| EP-2644379-B1 | Method of producing a planographic printing plate | FUJIFILM CORP (JP) | 2014-10-15 | — | — | EP | disclosed |
| WO-2014077995-A1 | SYNTHESIS OF MSE-FRAMEWORK TYPE MOLECULAR SIEVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-05-22 | — | — | WO | disclosed |
| WO-1993005040-A1 | AZABICYCLIC COMPOUNDS AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-18 | — | — | WO | disclosed |