Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972832 | 0.86 | HSP90AB1 (0.64) | HSP90AB1PDK2MEN1KMT2AALDH1A1 | |
| SCHEMBL111675 | 0.84 | HSP90AB1 (0.59) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29383556 | 0.84 | HSP90AB1 (0.59) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28738497 | 0.82 | MYC (0.52) | PDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13451780 | 0.82 | PDK2 (0.45) | HSP90AB1PDK2MEN1KMT2AALDH1A1 | |
| SCHEMBL28204560 | 0.82 | HSP90AB1 (0.42) | HSP90AB1PDK2MEN1KMT2AALDH1A1 | |
| Methane SCHEMBL28748613 | 0.82 | HSP90AB1 (0.57) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28116443 | 0.81 | PDK2 (0.44) | HSP90AB1PDK2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27873454 | 0.79 | CES2 (0.45) | PDK2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27567939 | 0.79 | ALDH1A1 (0.48) | HSP90AB1PDK2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084002-B | Preparation method of 2-hydroxyphenyl propiophenone | 常州瑞明药业有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-111454640-A | Pipeline anticorrosion epoxy powder coating containing hydroxyphenyl ketone compounds | 天津瑞远粉末涂料有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-104860803-B | Biphenyl ketonic compound and its preparation method and application | 暨南大学 | 2016-11-30 | — | — | CN | claimed |
| CN-104860803-A | Biphenyl compound and preparation method and application thereof | UNIV JINAN | 2015-08-26 | — | — | CN | claimed |
| CN-104262178-A | Synthesis method of propafenone hydrochloride | CHANGZHOU RUI MING PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-117264697-A | Extraction of polyunsaturated fatty acid from marine microalgae | 裘海红 | 2023-12-22 | — | — | CN | disclosed |
| CN-110615822-B | Macrolide compound, synthesis method, pharmaceutical composition and application thereof | 上海医药工业研究院有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-108084002-B | Preparation method of 2-hydroxyphenyl propiophenone | 常州瑞明药业有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-108084002-B | Preparation method of 2-hydroxyphenyl propiophenone | 常州瑞明药业有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-108084002-B | Preparation method of 2-hydroxyphenyl propiophenone | 常州瑞明药业有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-111454640-A | Pipeline anticorrosion epoxy powder coating containing hydroxyphenyl ketone compounds | 天津瑞远粉末涂料有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-107556320-B | Method for synthesizing 6H-isoindolo [2,1-a ] indol-6-one derivative | 复旦大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-105801550-A | Novel benzopyran kinase modulators | 理森制药股份公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-102812013-B | Novel benzopyran kinase modulators | RHIZEN PHARMACEUTICALS S.A. (CH) | 2016-05-25 | — | — | CN | disclosed |
| CN-104860803-A | Biphenyl compound and preparation method and application thereof | UNIV JINAN | 2015-08-26 | — | — | CN | disclosed |
| CN-104507922-A | Novel method for producing optically pure and optionally substituted 2- (1-hydroxy-alkyl) -chromen-4-one derivatives and the use thereof for producing medicaments | RHIZEN PHARMACEUTICALS SA | 2015-04-08 | — | — | CN | disclosed |
| CN-104262178-A | Synthesis method of propafenone hydrochloride | CHANGZHOU RUI MING PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-102812013-A | Novel Benzopyran Kinase Modulators | INCOZEN THERAPEUTICS PVT LTD | 2012-12-05 | — | — | CN | disclosed |
| WO-1993001158-A1 | METHOD FOR THE PREPARATION OF ARYLKETOAMINES | HOECHST CELANESE CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |
| US-4921881-A | COCONDENSATE OF TRIALKOXYVINYLSILANE AND TETRAALKOXYSILANE | DEGUSSA AKTEINGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |