Methane

Methane

SCHEMBL28748613

C.CCC(=O)c1ccccc1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.57
KDM4E B2RXH2 6/20 0.52
HPGD P15428 4/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
ALDH1A1 P00352 4/20 0.52
CA1 P00915 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA2 P00918 1/20 0.52
HMGB1 P09429 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
GAA P10253 2/20 0.52
MPO P05164 1/20 0.52
HIF1A Q16665 1/20 0.52
MAPT P10636 6/20 0.50
TSHR P16473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29383556 0.98 HSP90AB1 (0.59) HSP90AB1KDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL111675 0.98 HSP90AB1 (0.59) HSP90AB1KDM4EHPGDSMN1; SMN2ALDH1A1
Fumaric Acid SCHEMBL29445792 0.87 KDM4E (0.51) HSP90AB1KDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL11982582 0.86 HPGD (0.49) HSP90AB1KDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL17641364 0.85 SHBG (0.48) HSP90AB1KDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL13990159 0.84 L3MBTL1 (0.52) HSP90AB1SMN1; SMN2ALDH1A1MAPTTSHR
SCHEMBL9538711 0.82 HSP90AB1 (0.47) HSP90AB1KDM4EHPGDSMN1; SMN2ALDH1A1
SCHEMBL289555 0.81 CYP19A1 (0.58) KDM4EHPGDSMN1; SMN2ALDH1A1CA1
SCHEMBL1606580 0.81 HSP90AB1 (0.55) HSP90AB1HPGDALDH1A1CA1CA9
SCHEMBL598345 0.79 MEN1 (0.69) KDM4EHPGDSMN1; SMN2ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112585171-B Curable composition for pressure sensitive adhesives 3M创新有限公司 2023-04-28 CN disclosed
CN-1330674-C Multistage irradiation process for preparing acrylic adhesives 3M INNOVATIVE PROPERTIES CO LT (US) 2007-08-08 CN disclosed
CN-1606571-A Multi-stage irradiation process for producing of acrylic based adhesive 3M INNOVATIVE PROPERTIES CO (US) 2005-04-13 CN disclosed