Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541636 | 0.85 | MMP8 (0.49) | MMP8RAB9ANPC1CCKBRPOLB | |
| SCHEMBL9540255 | 0.84 | MMP8 (0.44) | KMT2AMMP8RAB9ANPC1CCKBR | |
| SCHEMBL9538003 | 0.82 | MMP8 (0.46) | KMT2AMEN1MMP8RAB9ANPC1 | |
| SCHEMBL9539180 | 0.82 | MMP8 (0.44) | MTNR1AMMP8RAB9ANPC1POLB | |
| SCHEMBL9538098 | 0.82 | MMP8 (0.44) | KMT2AMEN1MMP8MTNR1BRAB9A | |
| SCHEMBL8486077 | 0.82 | CCKBR (0.61) | KMT2AMEN1CCKBRMAPTALDH1A1 | |
| SCHEMBL9541051 | 0.80 | MMP8 (0.44) | KMT2AMEN1MMP8RAB9ANPC1 | |
| SCHEMBL9539323 | 0.80 | MMP8 (0.51) | MMP8RAB9ANPC1POLBMAPT | |
| SCHEMBL9699615 | 0.80 | CCKBR (0.56) | MTNR1APTPN1KMT2AMEN1MMP8 | |
| SCHEMBL9540074 | 0.78 | RAB9A (0.51) | KMT2AMEN1MMP8RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |