Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 8/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9538798 | 1.00 | SLC6A9 (0.47) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| Oxalic Acid SCHEMBL9535426 | 0.87 | SLC6A9 (0.49) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| Oxalic Acid SCHEMBL9535422 | 0.87 | SLC6A9 (0.49) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| Oxalic Acid SCHEMBL9535399 | 0.85 | SLC6A9 (0.47) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| Oxalic Acid SCHEMBL9535391 | 0.85 | SLC6A9 (0.47) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| Fumaric Acid SCHEMBL10382780 | 0.83 | SLC6A9 (0.49) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| SCHEMBL9535014 | 0.83 | SLC6A9 (0.55) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| Fumaric Acid SCHEMBL9635834 | 0.83 | SLC6A9 (0.58) | SLC6A9KDM4ESMN1; SMN2LMNAENPP2 | |
| SCHEMBL9535554 | 0.82 | SLC6A9 (0.52) | SLC6A9KDM4ESMN1; SMN2LMNAHRH1 | |
| SCHEMBL9684843 | 0.82 | SLC6A9 (0.64) | SLC6A9KDM4EHRH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |