Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15700931 | 0.82 | SMN1; SMN2 (0.42) | L3MBTL1LMNAALDH1A1TSHRGAA | |
| SCHEMBL8055385 | 0.79 | ALDH1A1 (0.43) | L3MBTL1LMNAALDH1A1TSHRGAA | |
| SCHEMBL6733610 | 0.78 | TAAR1 (0.50) | L3MBTL1LMNAALDH1A1TSHRGAA | |
| SCHEMBL6041511 | 0.76 | TAAR1 (0.42) | L3MBTL1ALDH1A1TSHRGAANPC1 | |
| SCHEMBL8905908 | 0.76 | SLC1A3 (0.42) | L3MBTL1ALDH1A1TSHRGAANPC1 | |
| SCHEMBL7444567 | 0.76 | MAPK1 (0.46) | ALDH1A1TSHRGAANPC1RAB9A | |
| SCHEMBL8906381 | 0.75 | TAAR1 (0.41) | L3MBTL1ALDH1A1TSHRGAANPC1 | |
| SCHEMBL5225326 | 0.75 | — | — | |
| SCHEMBL10689465 | 0.74 | LMNA (0.46) | L3MBTL1LMNAALDH1A1TSHRGAA | |
| SCHEMBL20912418 | 0.74 | POLB (0.53) | L3MBTL1LMNAALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |