Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386820 | 0.90 | MAOB (0.64) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL3693339 | 0.88 | MAOB (0.67) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL18121551 | 0.84 | MAOB (0.57) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL3813200 | 0.84 | MAOB (0.69) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL9622952 | 0.84 | MAOB (0.69) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL30957832 | 0.82 | POLB (0.62) | MAOBMEN1KMT2ARAB9APOLB | |
| SCHEMBL8338706 | 0.82 | FYN (0.61) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL2524920 | 0.82 | POLB (0.62) | MAOBMEN1KMT2ARAB9APOLB | |
| SCHEMBL12477879 | 0.82 | APP (0.61) | MAOBMEN1KMT2ASLC22A6SLC22A8 | |
| SCHEMBL4808985 | 0.81 | MAOB (0.53) | MAOBMEN1KMT2ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241043-B1 | NOVEL DIARYLALKANOIDS HAVING ACTIVITY AS LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-09-01 | — | — | EP | claimed |
| EP-0241043-A2 | Novel diarylalkanoids having activity as lipoxygenase inhibitors | WARNER-LAMBERT COMPANY (US) | 1987-10-14 | — | — | EP | claimed |