Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636292 | 0.89 | SLC6A9 (0.55) | SLC6A9TP53THRBMEN1KMT2A | |
| SCHEMBL9535297 | 0.85 | SLC6A9 (0.47) | SLC6A9TP53SLC6A2SLC6A4HRH1 | |
| SCHEMBL9535795 | 0.85 | SLC6A9 (0.45) | SLC6A9TP53SLC6A2SLC6A4HRH1 | |
| SCHEMBL9539478 | 0.84 | TP53 (0.44) | SLC6A9TP53SLC6A2SLC6A4HRH1 | |
| SCHEMBL10552594 | 0.83 | LMNA (0.54) | SLC6A9TP53THRBLMNAMAPT | |
| SCHEMBL10549493 | 0.83 | MAPT (0.50) | SLC6A9TP53SLC6A2SLC6A4MEN1 | |
| Oxalic Acid SCHEMBL10383154 | 0.82 | TP53 (0.44) | SLC6A9TP53SLC6A2SLC6A4HRH1 | |
| Oxalic Acid SCHEMBL9535399 | 0.82 | SLC6A9 (0.47) | SLC6A9TP53HRH1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9535391 | 0.82 | SLC6A9 (0.47) | SLC6A9TP53HRH1MEN1KMT2A | |
| SCHEMBL9535554 | 0.81 | SLC6A9 (0.52) | SLC6A9HRH1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |