Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 16/20 | 0.53 |
| ▸ | PNP | P00491 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539282 | 1.00 | MEN1 (0.53) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL9539314 | 1.00 | MEN1 (0.53) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL8884730 | 0.88 | BLM (0.67) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL9537422 | 0.84 | MEN1 (0.78) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL8990305 | 0.84 | MEN1 (0.78) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL8990372 | 0.84 | MEN1 (0.78) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| Phosphoric Acid SCHEMBL9538313 | 0.83 | MEN1 (0.77) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL15531833 | 0.80 | MEN1 (0.53) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL9019822 | 0.76 | MEN1 (0.48) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL2464875 | 0.76 | PDE3A (0.50) | MEN1ALDH1A1LMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |