SCHEMBL9539409

SCHEMBL9539409

CC(C)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6679201 0.92 LMNA (0.33) LMNA
SCHEMBL6678425 0.85 LMNA (0.37) LMNATHRB
SCHEMBL9538294 0.81 LMNA (0.42) LMNATHRB
SCHEMBL6676857 0.80 LMNA (0.32) LMNA
SCHEMBL22039247 0.77 LMNA (0.30) LMNA
SCHEMBL9540596 0.75 LMNA (0.41) LMNATHRB
SCHEMBL9539836 0.74
Perflubutane SCHEMBL111514 0.73 LMNA (0.54) LMNATHRB
Perflubutane SCHEMBL9051673 0.73 LMNA (0.54) LMNATHRB
SCHEMBL333119 0.72 LMNA (0.39) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993005200-A1 AZEOTROPE-LIKE COMPOSITIONS OF 1,1-DICHLORO-1-FLUOROETHANE AND PERFLUOROCARBONS AND OPTIONALLY NITROMETHANE ALLIED-SIGNAL INC. (US) 1993-03-18 WO disclosed